LPA and diabetic maculopathy: Notably, Deraza et al. reported that Lp(a) is significantly positively associated with central macular thickness, and higher Lp(a) levels, namely, 11.34 ng/mL, showed accuracy in predicting central macular edema (CME), indicating that Lp(a) can be used as a potential marker for diabetic maculopathy detection [16].