FGFR4 and neoplasm: Consistent with a role in PDAC metastasis, spatial FGFR4 expression from the single cell dataset in a UMAP plot showed significant overlap of FGFR4 expression with metastatic tumor cells as compared to primary tumor cells, indicating that FGFR4 expression is higher in metastatic cells as compared to primary tumor cells (Fig. 3B).