In the multivariable logistic regression adjusted for age, sex, tumor location, smoking and alcohol histories, higher dNLR was independently associated with advanced TNM stage (adjusted OR, 3.26; 95% CI, 2.09–5.10; p < 0.001), whereas higher NAT demonstrated an inverse association (adjusted OR, 0.54; 95% CI, 0.33–0.89; p = 0.015). This evidence concerns the gene BRD2 and neoplasm.