Furthermore, the analysis for single gene in the gene set revealed that low level expression of CD83, HLA-DMB, HLA-DQB1, HLA-DRA or HLA-DRB1, which was also detected in T-DCs (CD83 and MHCII), was significantly correlated with poor prognosis in ALL patients. Here, HLA-DQB1 is linked to acute lymphoblastic leukemia.