Additionally, serum miR-129-5p was significantly downregulated in PC cases with T3 or T4 stages compared to those with T2 stage & negatively correlated with NEAT1, BCL2, and TGF-β1, whereas NEAT1 was notably positively correlated with BCL2 and TGF-β1. This evidence concerns the gene TGFB1 and pachyonychia congenita.