Both lncRNA NEAT1 & miR-129-5p had powerful diagnostic performance for PC with specificity, sensitivity, and AUC of 93.3%, 83.3%, 0.89 at a cut-off value > 1.36 versus 100%, 95%, 0.96 at cut-off value ≤ 0.9, respectively. This evidence concerns the gene NEAT1 and pachyonychia congenita.