We compared a non-machine learning (non-ML) tool (ImageScope, Leica Biosystems) with a machine learning (ML) tool (Aiforia Create, Aiforia Technologies) on Ki67-stained slides from 10 low proliferative neuroendocrine tumor cases (Ki67 score < 5%, eight regions per slide). Here, MKI67 is linked to neuroendocrine neoplasm.