The results from the Western blot and immunohistochemical staining assays demonstrated an upregulation of E‐cadherin expression and a downregulation of ATP6V0E1 expression in the lung metastatic tumor tissues of the NAT10 knockout group compared to the control group, while overexpression of ATP6V0E1 diminished the regulatory effect of NAT10 knockout on both E‐cadherin and ATP6V0E1 expression (Figure S5I,J, Supporting Information). The gene discussed is CDH1; the disease is neoplasm.