In meningioma, molecules such as vascular endothelial growth factor (VEGF),81 matrix metalloproteinase‐9 (MMP9),82 hypoxia‐inducible factor alpha (HIF‐1α),83 and IL‐684 have been implicated in the development of peritumoral brain edema. The gene discussed is VEGFA; the disease is meningioma.