Interestingly, anti-CXCL4 antibodies correlated with IFN-α and TNF-α in the SSc plasma in our SSc cohort (anti-CXCL4 at T0 antibodies versus IFN-α at T0: r = 0.33, p = 0.038, n = 30; anti-CXCL4 at T0 versus TNF-α at T0: r = 0.33, p = 0.036, n = 30, by Spearman’s correlation test). Here, PF4 is linked to systemic sclerosis.