Following the established guidelines for this condition, a risk factor assessment was conducted, which led to the identification of a heterozygous mutation of factor V Leiden, with normal values of protein C and S, negative beta 2 glycoprotein 1 antibodies (IgM and IgG), negative cardiolipin antibodies (IgM and IgG), negative antiphospholipid antibodies (IgM and IgG), negative lupus anticoagulant ratio, antithrombin III within normal range (120.3%), and homocysteine levels within normal range (8.68 μmol/L). The gene discussed is CD40LG; the disease is systemic lupus erythematosus.