Referring to the biological role of IL-13 and its participation in the synthesis of serum IgE and in the expression of the CD80 molecule by podocytes [17,18,19], in patients with INS and a coexisting allergic process (food allergy, inhalation allergy), remission of kidney disease symptoms can be expected after successful elimination of the harmful allergen from the diet, thus ending the allergic inflammatory process in these patients. The gene discussed is IGHE; the disease is kidney disorder.