IFNG and gastric mucosa-associated lymphoid tissue lymphoma: Those that cause persistent inflammatory irritation include CagY (the Helicobacter pylori (H. pylori) CagY Protein), and it predominantly drives interferon-gamma (IFN-γ) and interleukin-17 (IL-17) secretion by gastric CD4+ T cells in H. pylori-infected patients with low-grade gastric MALT lymphoma [15].