IL6 and obstructive sleep apnea syndrome: Sloan et al. (2018) [22], which included healthy young adults undergoing progressive aerobic training, reported a greater reduction in IL-6 (SMD = −0.51), while Borges et al. (2019) [12], which involved participants with obstructive sleep apnea and a shorter intervention period, showed a slight increase (SMD = 0.26).