Additional AF-induced electrophysiological features observed in diabetic hearts include reduced atrial conduction velocity, resulting from impaired connexin distribution [61] and decreased peak sodium current (ΙNa,Peak) [58], and an increased incidence of arrhythmogenic Ca2+ release events, driven by CaMKII activation and increased oxidative stress associated with DM [24]. The gene discussed is CAMK2G; the disease is atrial fibrillation.