CASP3 and cancer: The apoptosis of MCF7 was induced, followed by the activation of pro-apoptotic genes (p53, Bax, Parp, Caspase-3, -8, -9) and the inactivation of antiapoptotic genes, such as the Bcl2 gene, in a study involving the growth inhibition and apoptosis of cancer cells by the ethyl 4-[(4-methylbenzyl)oxy] benzoate complex in vitro and in vivo [311].