This study was conducted to evaluate the distribution of FCGR2A-R131H, FCGR2B-I232T, FCGR3A-F158V and FCGR3B-NA1/NA2 polymorphisms in 126 patients with SLE (including 58 with LN) and 120 unrelated controls, in an indigenous African Caribbean population. The gene discussed is FCGR2A; the disease is lobular neoplasia.