Similarly, UTI significantly suppressed TNF-α levels (T4: −0.47 [−0.72, −0.22] P < 0.001; T5: −0.63 [−0.88, −0.38] P < 0.001), and this inhibitory effect was more pronounced at higher doses (T4: −0.84 [−1.09, −0.59] P < 0.001; T5: −1.03 [−1.28, −0.78] P < 0.001). This evidence concerns the gene TNF and bacterial urinary tract infection.