IFT57 KO in renal and retinal pigment epithelial cells disrupts primary cilia development, and fibroblasts derived from a patient with defective IFT57, causing Bardet-Biedl syndrome, exhibited fewer ciliated cells, more abnormal cilia, and impaired anterograde transport in primary cilia (Nitoiu, et al. 2025). This evidence concerns the gene IFT57 and Bardet-Biedl syndrome.