TGM2 and chronic kidney disease: The successful inhibition of the enzyme in our RWI rodent model with reduction of tubulointerstitial fibrosis adds to the compiling evidence showing the TG pathway is a causal link for the development of tubulointerstitial fibrosis and that this model mimics the expression of collagens and TG2 in a similar fashion as on the domestic cat with CKD, opening a door relevant for future therapeutic trials.