Infection with C. albicans has been reported to induce increased expression of autophagy markers LC3, ATG5, and LAMP1, and study also showed that apoptosis and necrosis was reduced in human vaginal epithelial cells overexpressed with wild-type ATG5 (Shroff and Reddy, 2018; Shroff et al., 2018). The gene discussed is ATG5; the disease is infection.