PRKAA1 and Hepatic steatosis: Maslinic acid (MA) (Liou et al., 2019a), Crocin (Luo et al., 2019), and Ursolic acid (UA) (Cheng et al., 2020) all improve hepatic steatosis and treat MAFLD by activating the AMPK pathway, promoting fatty acid oxidation, lipolysis, and inhibiting fat synthesis.