Khan et al. (2014) documented that topical application of SLM suppresses dermal inflammation in chemical-induced skin carcinogenesis by downregulating the NF-κB transcription factor. Moreover,Gheybi et al. (2023) demonstrated the anti-apoptotic effect of SLNPs against cadmium-induced apoptosis in MRC-5 and A-549 cancer cells by decreasing caspase-3 expression. The gene discussed is CASP3; the disease is cancer.