The most common medications observed were ACEIs, ARBs, and ARNIs at 51%, potassium supplements at 32%, and MRAs at 27%. Standard of care for treatment of hyperkalemia could include regular insulin 5 units or 0.1 units/kg (maximum 10 units IV push, dextrose 50% 25 mL or 50 mL IV push, calcium gluconate 1 g IV piggyback, nebulized albuterol 10 mg, or furosemide 40 mg or 80 mg IV push. In the SPS group, 60% (n=15) received at least one medication classified as standard of care. The gene discussed is INS; the disease is Hyperkalemia.