DUX4 and facioscapulohumeral muscular dystrophy: The scarcity of DUX4 expression and limited accessibility to viable muscle biopsies underscore the utility of patient‐derived induced pluripotent stem cells (iPSCs), which maintain donor‐specific genetic/epigenetic profiles, as physiologically relevant in vitro models for FSHD pathomechanistic studies. Here, we employed iPSC‐derived myotubes to investigate the pathogenesis of FSHD via single‐cell transcriptomic analysis, with the aim of identifying novel biomarkers.