Additionally, Ad‐infected tumor cells secrete cytokines, including type I interferons (IFNs) and tumor necrosis factor α (TNF‐α), along with chemokines such as CXC‐chemokine ligand 10 (CXCL10), which all result in infiltration of innate immune cells such as DCs, macrophages, natural killer (NK) cells, and neutrophils to the tumor [5]. This evidence concerns the gene TNF and neoplasm.