HBG2 and methemoglobinemia: The bedside echocardiography and ECG ruled out cardiac abnormalities, while laboratory investigations revealed a significant elevation in methemoglobin levels, confirming the diagnosis.[9] Management of acquired methemoglobinemia involves discontinuation of the offending agent, in this case, dapsone, and administration of supplemental oxygen to improve tissue oxygenation.[5,10] Methylene blue, a reducing agent, is often used to accelerate the conversion of methemoglobin back to functional hemoglobin.