It also plays a role in the development of oligodendrocytes and is considered a candidate gene for features related to myelin integrity in schizophrenia.[30] STAT3 is involved in critical physiological and pathological processes, including cell proliferation, differentiation, survival, apoptosis, transformation, and cellular immunity, and is classified as a proto-oncogene.[31] Additionally, mutations in the RELA gene may be linked to prepulse inhibition and startle response in schizophrenia.[32,33]. The gene discussed is STAT3; the disease is schizophrenia.