Although AVS is the most commonly used technique for subtyping, it has significant limitations, and many factors can result in falsely negative AVS findings, including non-stimulation sampling, stress, hypokalemia, mineralocorticoid receptor antagonists, and cortisol co-secretion.[7] Additionally, published literature has indicated that anatomical abnormalities of the adrenal veins may significantly affect the accuracy of AVS results. Here, NR3C2 is linked to Hypokalemia.