Markers such as CA125, CEA, SCC, and NSE are particularly prone to this issue.[16] Conducting clinical imaging screenings on dialysis patients to detect renal cancers in their early stages would be extremely advantageous.[17] It should be noted that the effectiveness of CT, MRI, and US in identifying renal cancer in kidneys with multiple cysts is frequently questionable. Here, SERPINB3 is linked to renal carcinoma.