TXN and renal carcinoma: Patients with weakened immune systems are susceptible to suppressed defense responses and the unchecked growth of oncogenic viruses due to impaired immune monitoring in their tissues.[12] Additionally, the category of immunosuppressive drugs could influence the magnitude of the elevated risk for tumors.[13,14] Furthermore, the heightened levels of oxidative stress, the upsurge in antioxidant proteins, peroxiredoxin, and thioredoxin, are regarded as potential factors contributing to the increased prevalence of renal cancer in ESRD patients compared to those with normal renal function.[15]