SLC7A11 and neurodegenerative disease: Ferroptosis, a form of regulated cell death characterized by the accumulation of lipid hydroperoxides to lethal levels, was linked to degenerative diseases.[18] SLC7A11 is responsible for taking cystine from the extracellular environment and converting it to cysteine in the cytoplasm through a reduction reaction that consumes NADPH.[25–27] Then we use cysteine to make glutathione.