Using various analytical methods, we identified the genomic and functional networks and pathways associated with the expression of CD318 and its involvement in the immune microenvironment in various cancers such as colorectal adenocarcinoma (COAD), cervical squamous cell carcinoma (CESC), lung adenocarcinoma (LUAD), and pancreatic adenocarcinoma (PAAD). The gene discussed is CDCP1; the disease is cervical squamous cell carcinoma.