The area under the ROC curve (AUC) for ADAM15 (0.5070, p > 0.05) was lower than for the classical tumor markers (CA19-9—0.5617, p > 0.05; CEA—0.7519, p < 0.001) and the marker of inflammation (CRP—0.8220, p < 0.001) in the diagnosis of CRC (Figure 2). This evidence concerns the gene CEACAM5 and neoplasm.