Among all proteins tested, only the concentrations of CEA (p = 0.004, OR = 1.428) and CRP (p < 0.001, OR = 1.392) were associated with significantly increased CRC prediction, which was also proved in the multivariate model of CEA (p = 0.018, OR = 1.352) and CRP (p = 0.001, OR = 1.341) (Table 7). The gene discussed is CRP; the disease is colorectal carcinoma.