AKT3 and psoriasis: Xian et al. detected via qRT-PCR and RNAscope® in the skin tissue of psoriasis patients upregulated levels of AGAP2-AS1, a long non-coding RNA with implications in the biological mechanisms of psoriasis pathogenesis; it acts as a competitive endogenous RNA by sponging miR-424-5p to upregulate AKT3 and activate AKT/mTOR pathway, thus promoting cellular proliferation in keratinocytes [19].