MEG3 and psoriasis: Jia et al. also surveyed the role of MEG3 in psoriasis pathogenesis, applying qRT-PCR to measure the mRNA levels in a cell model for in vitro study; their findings were congruent: MEG3 inhibited cell proliferation and promoted apoptosis in activated cells by regulating miR-21 and suppressing caspase-8 expression [23].