The chronically elevated PTH in SHPT leads to a cascade of mineral and bone disorders, as well as systemic complications, known collectively as CKD–mineral bone disorder, namely: high-turnover renal osteodystrophy, intractable bone pain and fractures, extensive vascular/valvular calcifications, refractory anemia and, ultimately, increased cardiovascular and all-cause mortality [3]. Here, PTH is linked to chronic kidney disease.