AGT and COVID-19: Thus, while ADAM10, ADAM17, Ang I, and Ang II may play a role in the pathophysiology of COVID-19, the lack of symptom progression in our participants underscores the need for continued research into the biochemical impact of SARS-CoV-2-induced dysregulation of RAAS, not only in blood but also across cardiovascular, renal, and pulmonary systems.