Additional predictors included heart failure with a preserved ejection fraction (HFpEF) and NT-proBNP > 3.000 pg/mL (HR 5.02; p = 0.002), postoperative low-cardiac-output syndrome (LCOS) (HR 4.28; p = 0.001), perioperative stroke (HR 3.47; p = 0.021), and a minimally invasive thoracotomy (MT) approach (HR 1.84; p = 0.049). The gene discussed is NPPB; the disease is heart failure.