The results of a large-scale genome-wide association study (GWAS) conducted by Gorsic et al. [28] highlight the significant involvement of multiple genes—such as FTO, INSR, and MC4R—in the pathogenesis of polycystic ovary syndrome (PCOS), regardless of the diagnostic criteria applied (Rotterdam, NIH, or AES). Here, MC4R is linked to polycystic ovary syndrome.