The frequencies of HSD17B13 AG and AG+GG genotypes were also higher in healthy controls vs. the VIRAL-HCC group (OR 1.71; 95% CI 1.13–2.60; p = 0.008, and OR 1.62; 95% CI 1.09–2.41; p = 0.01, respectively). This evidence concerns the gene HSD17B13 and hepatocellular carcinoma.