Several dysregulated miRNAs identified in follicular cysts, including bta-miR-18a, bta-miR-30e-5p, and bta-miR-15b, are well-documented modulators of cellular stress responses (GO:0033554), insulin signaling (GO:0008286), and apoptosis (GO:0006915), processes frequently disrupted in both OFCs and PCOS [39,40,41,42,43,44,45,46,47,48,49,50,51,52,53]. This evidence concerns the gene INS and polycystic ovary syndrome.