Given the relatively low number of DMD patients with exon 44–45 deletions and a link between this deletion and a milder phenotype, exon 44 skipping in DMD boys who already have an exon 45 deletion or another exon 44-skipping amenable deletion is thought to result in the restoration of the reading frame and yield a shortened but partially functional dystrophin protein [34]. Here, DMD is linked to Duchenne muscular dystrophy.