IL33 and inflammatory bowel disease: Some of these polymorphisms are located within or near genes that encode or regulate cytokines characteristic of the Th2 immune response, including IL-4, IL-5, IL-13, thymic stromal lymphopoietin (TSLP), and IL-33 [101], suggesting that genetic susceptibility to IBD in this breed may be linked to the expression of specific cytokines that contribute to dysregulated immune responses.