Some of these polymorphisms are located within or near genes that encode or regulate cytokines characteristic of the Th2 immune response, including IL-4, IL-5, IL-13, thymic stromal lymphopoietin (TSLP), and IL-33 [101], suggesting that genetic susceptibility to IBD in this breed may be linked to the expression of specific cytokines that contribute to dysregulated immune responses. Here, TSLP is linked to inflammatory bowel disease.