IL36RN and psoriasis 14, pustular: Since microRNAs and lncRNAs regulate various cellular processes, their differential expression patterns may indicate their potential role as biomarkers and therapeutic targets [20].Thus, the aim of the present study was the investigation of macromolecular interaction networks contributing to DITRA pathogenesis, focusing on the impact of ncRNAs on IL36RN interactome towards identifying potential biomarkers, risk factors and therapeutic targets.