When comparing the prevalence of specific genes and comorbidities, we found the following associations in AR RP: CRB1 was statistically associated with ERM (p = 0.003), EYS with cataract (p = 0.001), PROM1 with CNV (p = 0.0026), and USH2A with macular hole (p = 0.01). The gene discussed is USH2A; the disease is macular holes.