In addition, the association of molecular subtypes of ALL with genetic ancestry reveals that Amerindians are associated with a low probability of subtypes ETV6::RUNX1, BCR::ABL1, TCF3::PBX1, and KMT2A, and show an increased propensity to other molecular subtypes such as DUX4, PAX5alt, and ETV6::RUNX1-like [15]. This evidence concerns the gene TCF3 and acute lymphoblastic leukemia.