To explore the clinical significance of the seven prognostic risk model-related genes, used clinical specimens from the HPA (Human Protein Atlas) database; HPA analysis showed that the protein levels PASK, PSENEN, and RCC2 were shown in Breast cancer tissues compared to normal Breast tissue and MTFP1, PSME2, MEA1, and SH2D2A were not found in database. This evidence concerns the gene RCC2 and breast cancer.