We analyzed a panel of 13 BCC marker genes previously identified in an Italian study [24], including PTCH1, SMO, GLI1, CSMD1, CSMD2, NOTCH1, NOTCH2, TP53, ITIH2, DPP10, and STEAP4, as well as promoter mutations in TERT and DPH3. This evidence concerns the gene NOTCH2 and skin basal cell carcinoma.