The factors that enhance EDKA appearance in the context of the use of SGLT2 inhibitors are represented by processes that enhance ketone body synthesis (anorexia, ketogenic diet), dehydration (alcohol consumption or diuretic drugs), and processes that increase oxidative stress and cause discharges of catecholamines and corticosteroids (infections, postoperative and intraoperative stress, stroke) [98,105,106,107]. Here, SLC5A2 is linked to infection.