Different subtypes known so far for B-ALL include DUX4-r, ETV6-RUNX1, ETV6-RUNX1-like, hyperdiploid, KMT2A-r, low hyperdiploid/near triploid, near-haploid, MEF2D-r, PAX5-alt, PAX5-P80R, Ph-like, Ph-positive, TCF3-HLF, TCF3-PBX1, ZNF384-r, and iAMP21 [137]. This evidence concerns the gene PAX5 and precursor B-cell acute lymphoblastic leukemia.