Interestingly, deletion of CaMKK2 did not attenuate the immunosuppressive function of MDSCs but induced apoptosis [107], indicating that decreased tumor growth occurred not because of the diminished suppressive function of MDSCs but by impaired expansion of MDSCs, due to the loss of CaMKK2, in the tumor pathology. The gene discussed is CAMKK2; the disease is neoplasm.