MTOR and neoplasm: Another similar report [34] revealed that M-MDSCs, defined as CD45+CD11b+Ly6Chigh and Ly6G−, from tumor tissues of mice showed overexpression of mTOR and increased glycolysis, as demonstrated by upregulated expression of glycolysis-associated genes and increased absorption of 2-(N-(7-Nitrobenz-2-oxa-1,3-diazol-4-yl)Amino)-2-Deoxyglucose (2NBDG), an indicator of glucose uptake.