KEGG pathways unique to the GS 8–9 U-EVs were related to gastric acid secretion, proteasome, apoptosis, oxytocin signalling pathway, arrhythmogenic right ventricular cardiomyopathy, and several neurodegenerative diseases (Parkinson’s disease, amyotrophic lateral sclerosis, prion disease, Alzheimer’s disease, and spinocerebellar ataxia), which may be of interest in relation to recent reports linking these conditions [55,56] and possible common therapeutic targets [57], or possibly linked to perineural invasion, associated with more aggressive PCa [58,59]. This evidence concerns the gene OXT and Parkinson disease.