RUNX3 and posterior cortical atrophy: Additional top 25 scoring pathways were regulation of RUNX3 expression and activity, which plays a role in metastasis and angiogenesis in PCa [68]; translocation of GLUT4 to the plasma membrane; platelet degranulation; the recycling pathway of L1; and regulation of AURKA during mitotic entry and in early mitosis by FBXL7, with AURKA identified as a critical gene for PCa progression [69,70].