Elongation factor 1-alpha has roles in translation and possible associations with PCa progression [23], while vesicle-fusing ATPase is important for vesicle-mediated transport, with associations in oesophageal squamous cell carcinoma [24], and phosphopyruvate hydratase (enolase) is a key glycolytic enzyme and metalloenzyme with roles in cancer development [25]. The gene discussed is HK1; the disease is cancer.